Acute myocardial infarction ; cardiogenic shock ; congenital QT syndrome ; do not initiate for angina if heart rate below 70 beats per minute ; do not initiate for chronic heart failure if heart rate below 75 beats per minute ; immediately after cerebrovascular accident ; patients dependent on pacemaker ; second- and third-degree heart block ; severe hypotension ; sick-sinus syndrome ; sino-atrial block ; unstable angina ; unstable or acute heart failure.
Atrial fibrillation or other arrhythmias treatment ineffective ; elderly ; in angina, consider stopping if there is no or limited symptom improvement after 3 months ; intraventricular conduction defects ; mild to moderate hypotension avoid if severe ; retinitis pigmentosa. Arrhythmias ; atrioventricular block ; dizziness ; headache ; hypertension ; vision disorders.
Abdominal pain ; angioedema ; constipation ; diarrhoea ; eosinophilia ; hyperuricaemia ; hypotension ; muscle cramps ; nausea ; QT interval prolongation ; skin reactions ; syncope ; vertigo. Manufacturer advises caution in moderate impairment; avoid in severe impairment—no information available. See Prescribing in renal impairment. Monitor regularly for atrial fibrillation consider benefits and risks of continued treatment if atrial fibrillation occurs. Ejection fraction is a measurement of how much blood is pumped from the left ventricle with each contraction of your heart.
Your healthcare provider decides the right dose for you to take. This dose might be changed, based on your heart rate. This medication could be added to your treatment. When used with other heart failure medications, it may:. If you miss a dose and it is more than 4 hours until your next dose, take the missed dose then take your usual dose at the usual time.
If you miss a dose and it is less than 4 hours until your next dose, just take your next scheduled dose. Do not take the missed dose. Never take 2 doses at the same time. Get up slowly when changing position, such as moving from lying to sitting or sitting to standing.
Balance rest with activity. If your heart rate is less than 50 beats a minute, your healthcare provider might lower the dose or ask you to stop taking it.
Contact your healthcare provider. You might need your heart rhythm checked with heart tracing electrocardiogram or ECG. If you have questions about taking your medications, or missed doses, contact your pharmacist, your healthcare provider, or call Eating a healthy diet that is lower in fat, especially saturated and trans fats, being smoke free , limiting alcohol use , being physically active and reducing stress are also important in lowering the risk of heart disease.
Talk to your healthcare practitioner about how you can achieve these lifestyle changes. Your healthcare provider or pharmacist are your best sources of information. You can also learn more about medications at any of these trusted sites. Health Canada - Drugs and Health Products Provides health and medical information for Canadians to maintain and improve their health.
Learn more about:. Your ministry of health also offers health resources in your province or territory. Living Well with Heart Disease is a comprehensive guide for heart patients like you, your family and friends to improve your success of recovery, understand the diagnosis and treatment you will receive and make healthy changes to your lifestyle. Ivabradine is used to treat certain adults with heart failure condition in which the heart is unable to pump enough blood to the other parts of the body to decrease the risk that their condition will worsen and need to be treated in a hospital.
It is also used to treat a certain type of heart failure in children 6 months of age and older due to cardiomyopathy a condition in which the heart muscle becomes weakened and enlarged. Ivabradine is in a class of medications called hyperpolarization-activated cyclic nucleotide-gated HCN channel blockers. It works by slowing the heart rate so the heart can pump more blood through the body each time it beats. Ivabradine comes as a tablet and as an oral solution liquid to take by mouth.
It is usually taken with food twice a day. Take ivabradine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ivabradine exactly as directed. Do not take more or less of it, or take it more often than prescribed by your doctor. Some ivabradine tablets come with a line down the middle. If your doctor tells you to take half a tablet, break it carefully on the line.
Take half the tablet as directed, and save the other half for your next dose. Use an oral syringe measuring device and a medicine cup to accurately measure and take your dose of ivabradine solution. Ask your pharmacist for a medicine cup if one is not included with your medication. Your pharmacist will give you an oral syringe that works best to measure your dose. Empty all of the solution from the ampule s into the medication cup. Measure your dose of from the medication cup using the oral syringe.
Follow the manufacturer's instructions about how to use and clean the oral syringe. Ask your doctor or pharmacist if you if you have any questions. If you vomit or spit out after taking ivabradine, do not take another dose. Continue your regular dosing schedule. Your doctor may increase or decrease your dose after 2 weeks depending on how well the medication works for you, and the side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with ivabradine.
Ivabradine controls the symptoms of heart failure but does not cure it. Continue to take ivabradine even if you feel well. Do not stop taking ivabradine without talking to your doctor.
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