The drug was available in 10 milligram tablets under the brand name Numorphan until it was taken off in the market in the s. Oxymorphone can also be administered as its hydrochloride salt via injection i. IV drip or suppository. Injecting Opana intravenously may cause the user to develop a serious blood disorder that can lead to kidney failure or deathf kidney failure requiring dialysis and at least one death have been linked to injection of Opana into the bloodstream.
The blood disorder , thrombotic thrombocytopenic purpura TTP , causes blood clots to form in blood vessels throughout the body. Blood flow to the kidneys, brain, heart and other organs may limited or stopped altogether. The blood clots can also cause bleeding under the skin and internal bleeding throughout the body. In addition to kidney failure, possible effects of the disorder include stroke and brain damage.
Opana is an extended-release opioid painkiller that contains oxymorphone. Like OxyContin, it carries a high risk of abuse, addiction and overdose.
Since , law enforcement authorities have seen a rise in the addiction to Opana. The growing popularity of the drug has been attributed to the reformulation of OxyContin to make it harder to inject or snort.
When injecting OxyContin became too difficult, many drug abusers discovered that they could crush Opana and snort or inject it for a heroin-like high. Prescription drug abusers who switch from OxyContin to Opana are often unaware that Opana is more potent per does and carries a greater risk of overdose. Endo Pharmaceuticals, the maker of Opana, has developed a crush-resistant version that has been approved by the FDA. Although the new formula is slated to replace the older extended-release version, many pharmacies still stock the older version.
In the interim, the FDA is making health care professionals and others aware of the particularly serious risks associated with the abuse of this product. The FDA will continue to examine the risk-benefit profile of all approved opioid analgesic products and take further actions as appropriate as a part of our response to this public health crisis.
The FDA, an agency within the U. Department of Health and Human Services, promotes and protects the public health by, among other things, assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. For Immediate Release: June 08, He said people start with a clear idea, and they become addicted.
In his book, he says that they think like addicts and act like addicts. He says you are a victim if you have an alcoholic loved one in your home because he or she will exploit and abuse you. The physical effects of opana are horrifying. He says they will leave you with what I call the Afterburn effect because you will be so depressed after coming home from work spending all day crying yourself to sleep.
He says one person in five will have an addiction problem and the normal reaction to this is to bottle it up and not go anywhere.
However, if you have a support group, if you can talk to them about your feelings, ask questions about your addiction, and if you know where to look for help, you can recover and live a productive and happy life.
There is some evidence that opana increases dopamine levels in the brain, which means that users may experience euphoria feelings. The drug has also been shown to increase heart rate and blood pressure, so if you are a person who is currently experiencing any of these symptoms, it would be advisable to consult your doctor before taking Opana.
Opiate drugs affect the brain through their chemical structures. These structures include opiate receptors, opiate oxidase ORO proteins, and mu-opioid molecules. These opana compounds are all involved in the opiate drug interaction, and receptors determine how the drug gets into the brain and how it acts. When the receptors are broken down The opiate drugs move out of the body and are excreted through urine, feces, and the skin.
WebMD states that more than million individuals suffer from severe pain in the USA and when they visit professional doctors they prescribe them at least one opiate from the family of pain killers like Opana. Others are afflicted with a certain kind of discomfort. According to the Huffington Post , people suffering from some type of mental illness are in numbers of However, in cases of poly-drug trafficking, the main distinction in abuse signs is the prevalence of other drugs.
Abusing Opana has far-reaching effects that even drug addicts are unaware of. Many that misuse Opana ER extended-release as an IV drug run the risk of blood-borne infections including hemolysis and thrombocytopenia, according to the Blood Journal.
Respiratory depression, which may lead to death, is one of the immediate threats of drug abuse. The rising trend of Opana abuse has resulted in a substantial increase in harmful effects associated with its use. To treat any problem with opana, the opioid abuser must avoid abusing the drug and begin detoxing. According to the Substance Abuse and Mental Health Services Administration , , patients were admitted to rehabilitation centres around the country which were non-heroin drug abusers in
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